Healthcare: Genomic Patient Matching for Clinical Trials

The solution required an ML platform capable of ingesting and processing next-generation sequencing data, including whole exome sequencing and targeted gene panels, matching patient molecular profiles against clinical trial eligibility criteria. The system needed to integrate with Epic EMR infrastructure to pull patient demographics, treatment history, diagnosis codes, and lab results alongside genomic data from the institutional biobank. Explainability was non-negotiable, with every patient-trial match requiring documented reasoning that clinical researchers and IRB reviewers could audit for FDA compliance. The platform needed human-readable explanations detailing which genomic markers, prior treatments, and clinical factors contributed to eligibility. Real-time processing was essential, enabling oncologists to identify trial-eligible patients during treatment planning with results returned in under 10 seconds across 100,000+ patient records and 40+ active trials.